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Bladder pills and dementia risk

Dr. Fernando Gómez Sancha · Urologist · Medical Director of ICUA

Video published: · 0:35

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Original video description

Antimuscarinics for the bladder (solifenacin, oxybutynin, tolterodine…) block acetylcholine throughout the body: dry mouth, constipation, blurred vision and, in older people, cognitive decline. Studies link long-term use with a higher risk of dementia. Discuss it with your doctor.

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Side effects, there's a problem here. Anti-muscarinics block acetylcholine, not only in the bladder, but throughout the body, causing dry mouth, less saliva is produced, which is often very annoying, constipation, blurred vision, and in older people it can cause or contribute to cognitive decline. This last point is very important.

There are studies linking the long term use of anticholinergics with an increased risk of dementia. It's not cause for alarm, but it's something you should know and discuss with your doctor.